Should moles be removed or not? What kind of moles must be removed? How can I monitor myself to determine whether a mole is malignant or not? Below I will give you a brief and concise introduction to the knowledge of moles. 1. First of all, there are different numbers of moles on everyone’s body surface, which are discovered at birth or grow later, and there are about 20 moles on average in everyone’s body. The vast majority of moles will not undergo malignant changes, and only a very small number of moles will turn into melanoma. In the past, melanoma was considered to be highly malignant, and therefore treatment for melanoma was rather “cruel”, with amputation of the lower limbs of toes found to be malignant. Nowadays, with the increase of treatment experience and technological progress, the treatment means of malignant nevus are also progressing. Therefore, there is no need to worry too much about the possibility of malignant transformation of moles. 2, the malignant transformation of nevus is particularly manifested in: (1) the growth speed is obviously accelerated; (2) local itching, pain and other symptoms; (3) local ulceration; (4) nevus with unclear boundary and infiltrative growth. Therefore, self-monitoring can be carried out according to the above characteristics, of course, there is no “absolute” existence in medicine, nevus malignancy may not appear the above symptoms, and timely appearance of the above symptoms may not necessarily appear malignancy. 3.What are the risk factors of nevus malignancy? It mainly includes the following points: repeated friction, ultraviolet radiation, mucous membrane parts and so on. Therefore, moles on the palms of hands, soles of feet, mucous membrane parts (lips, mouth, vulva) must be excised, and repeated friction parts, such as male beard parts, waistband, bra band parts should also be excised. Facial moles should also be removed because they are exposed to ultraviolet rays and affect the aesthetics. 4. Should moles be excised or removed by laser? After excision, the specimen can be sent for pathological examination to get accurate results, which is the safest way; however, surgical scar will remain after excision. Plastic surgery can hide the scar to the greatest extent possible, but it cannot remove the scar completely. Laser mole removal is suitable for superficial and small-sized moles, and the advantage is that as long as the peeling depth is properly mastered, the prognosis basically leaves no trace. Therefore, both of them have their own advantages and should be specifically analyzed for each patient’s specific situation.