Mr. Wang has a black mole on his face, it is not big and does not affect his eyesight, but his wife went to tell his fortune and the fortune teller said that this mole on Mr. Wang’s face foretells his life as a second wife. Mr. Wang’s wife thought the mole was ominous and dragged Mr. Wang to a nail salon near his home to have it painted off with chemicals. To get rid of a mole, surgical excision is the best method, which can completely remove the mole at one time and the cosmetic stitching method does not affect the beauty. Methods such as laser, freezing and chemical drugs may not be complete, and if you repeatedly remove moles for many times, it is a bad stimulation to the moles and it is very likely to induce malignant change of moles. There are many kinds of mole removal methods, such as laser, freezing, ionization, chemical drugs and surgical excision. Removing moles with chemical drugs is a very common means of removing moles among the people. Professor Liu Linshan, director of the Department of Dermatology of the First Affiliated Hospital of Zhengzhou University, suggests that it is better to choose surgery to remove moles in a regular hospital and then do a pathological test to screen the benign malignancy of moles. Professor Liu Linshan explained that nevus is a kind of benign tumor on the surface of human skin, and some of them can become malignant. Nevi can be divided into intradermal nevus, junctional nevus and mixed nevus. Intradermal nevus does not have the tendency to become malignant, so it is not necessary to take care of it if it does not affect the beauty. If a nevus gradually becomes larger, has dilated blood vessels, increases pigmentation, and has inflammatory reactions or small satellite nevi, it indicates the possibility of malignant transformation and should be treated by a doctor in time.