In fact, progesterone taken before or after meals does not affect the absorption of the drug, does not affect the efficacy of the drug, but there are some patients because of chronic gastritis or gastrointestinal relatively sensitive, relatively weak, oral progesterone pills may lead to gastrointestinal tract irritation, so there will be symptoms of upper abdominal discomfort, such patients can be given about an hour after the meal, so as to reduce the gastrointestinal tract This will reduce the irritation of the gastrointestinal tract. In addition, progesterone should be taken with caution if the patient has hypertension or kidney disease. If you have thrombotic diseases, such as thrombophlebitis and cerebrovascular diseases, you must take it carefully. This drug belongs to the progestin class, which mainly has the effect of regulating menstruation in clinical practice, and has the effect of antifetus and menstruation, so it should be given only under the guidance of a doctor.