Keratinized eczema generally refers to chronic eczema, mostly from acute, subacute eczema did not cure in time, repeated episodes of migration. Chronic eczema does not have obvious blisters, vesicles oozing and other manifestations, mainly for the local skin keratinization, thickening, clinically affected skin infiltration of dark red spots with scales, scratches, hyperpigmentation and so on. Chronic eczema is mostly due to the original acute, subacute eczema without timely treatment or repeated episodes of transformation, or due to the local long time slight stimulation at the beginning of the chronic process. Chronic eczema is recommended to the regular hospital dermatology consultation, can be used under the guidance of the doctor external glucocorticoid such as fluticasone propionate cream, halometasone cream, etc., can be combined with moisturizers and keratolytic agents, such as urea ointment, salicylic acid ointment and so on. Drugs should be used strictly in accordance with medical advice, and if there is any discomfort, consult your doctor promptly.