The BCG vaccine is effective when the pus is squeezed. However, usually BCG pus should not be squeezed because it is easily co-infected. The BCG vaccine is an attenuated, live tuberculosis contact vaccine that is given to babies within 24 hours of birth. The growth of pus after BCG vaccination indicates that the vaccination has been successful, and the BCG vaccine is also effective if the pus is squeezed at this time. Four to six weeks after vaccination, small localized ulcers will form, and care should be taken to keep the wound free from infection and to keep the area clean and dry. The pus is squeezed may induce infection, we should use iodophor to disinfect the pus rupture place in time, and do a good job of daily care measures to ensure that the child’s pus rupture place skin clean and hygienic. After the BCG pus is squeezed, it is recommended to check whether the body produces antibodies against tuberculosis bacilli. After the BCG pus is squeezed out, you can go to the hospital for examination, and it is not recommended to delay.