Metronidazole and clindamycin can be used at the same time. Metronidazole nitroimidazole antibacterial drugs, widely used in the treatment of anaerobic infections, but also for intestinal and extraintestinal amebiasis, vaginal trichomoniasis and other diseases. Some patients will have nausea and vomiting, abdominal pain, headache and other discomforts after taking it, and it is forbidden for those who have severe liver and kidney function damage, pregnant and lactating women, and those who are allergic to metronidazole. Clindamycin is a lincosamide antibiotic, with high antibacterial activity against aerobic gram-positive cocci and some effect on anaerobic bacteria, commonly used in otitis media, pelvic infection and other diseases. Some patients will be nausea and vomiting, leukopenia and other adverse reactions, lincomycin or clindamycin allergy is prohibited. Metronidazole and clindamycin are used together without mutual side effects, and are more effective for pelvic inflammation and mixed vaginitis. It is recommended that you visit a hospital if you feel unwell, and accept the guidance of a professional doctor, so as to avoid the irreversible consequences of blindly using medication on your own.