The efficacy of Zixuexuan for pediatrics is to clear heat and open the orifices, antispasmodic and tranquilize the mind. Pediatrics need to be careful with the use of drugs, need to be under the guidance of a doctor. Zixue San, composed of gypsum, northern cold water stone, talc, magnetite and so on. Used for heat into the pericardium (heat evil invasion of the pericardium), heat moving liver wind evidence, symptoms of high fever and irritability, delirium (confusion, babbling), convulsions (with dizziness, convulsions, convulsions as the main manifestations of pediatric diseases) convulsions, rash epistaxis (vomiting blood, nosebleed), red urine and constipation. Zixue San is contraindicated in pregnant women. This product contains cinnabar and should not be taken in excess for a prolonged period of time, and should be used with caution in patients with hepatic or renal insufficiency. The adverse effects of Zixue San are not clear. If children have any discomfort, it is recommended to consult a doctor promptly. If medication is needed, it should be diagnosed by a doctor and regulated according to the doctor’s instructions.