For antihypertensive drugs that lower the heart rate, the most commonly used are usually beta-blockers, and none of the other antihypertensive drugs have a significant effect on lowering the ventricular rate. Commonly used are atenolol, also known as aminoglutethimide, a selective cardiac beta-blocker with no endogenous inhibition of sympathetic activity. Alternatively, metoprolol, often known by the trade name betalactam, can be applied, and is a highly selective beta-blocker that can treat hypertension, angina pectoris, myocardial infarction, and arrhythmias. Sotalol hydrochloride, which can be applied to patients with life-threatening tachyarrhythmias, such as sustained ventricular tachycardia, and propranolol hydrochloride, which can be used for hypertension, angina pectoris, arrhythmias, hypertrophic cardiomyopathy, adrenal pheochromocytoma, and hyperthyroidism, can also be applied.