Low differential pressure usually refers to the relatively low difference between systolic and diastolic blood pressure, also clinically referred to as low pulse differential pressure, the normal value of pulse differential pressure between 20-60 mmHg, less than 20 mmHg is called low differential pressure. The cause of low pulse pressure difference may be related to the physiological factors of somatic hypotension, and may also be related to hypertension, hyperlipidemia, diabetes, atherosclerosis and other pathological factors. A, physiological factors: institutional hypotension: common in some elderly people and some women, this group of people may appear physiological low pulse pressure difference, the main reason is due to weakness, malnutrition, thin body, generally no discomfort, daily need to pay attention to nutrition, enhance their own physical fitness. Second, pathological factors: 1, atherosclerosis: atherosclerosis may also be manifested as a small differential pressure, mainly seen in young and middle-aged people with good vascular elasticity, due to good vascular elasticity, will lead to a sustained increase in diastolic blood pressure, in the clinic is also called diastolic hypertension; 2, hypertension: generally common in normal systolic blood pressure, while diastolic blood pressure is often significantly elevated, thus causing low pulse pressure, in Young and middle-aged hypertensive patients are more common; 3, hyperlipidemia: patients with hyperlipidemia, because the blood viscosity is higher, so when measuring blood pressure, may also lead to an increase in diastolic blood pressure and cause low pulse pressure. There are many other causes of low pulse pressure difference, such as diabetes, aortic stenosis, chronic heart failure and other diseases common in the elderly, may occur in the case of low pulse pressure difference. In addition, relatively poor lifestyle habits, smoking, alcoholism, obesity or when it leads to insulin resistance, can also have a low pulse pressure difference.