Sperm not liquefied is usually semen not liquefied, may be the seminal vesiculitis and prostatitis and other causes, the patient can follow the doctor’s instructions to use cefuroxime, ofloxacin and mifepristone and other drugs to regulate. 1. Spermatitis: After the patient has suffered from spermatitis, the inflammation of the seminal vesicles can make the secretion of the above factors impaired, resulting in an increase in the coagulation factor, and leading to semen non-liquefaction disorder. This time there will be semen not liquefied, the patient can follow the doctor’s instructions to use cephalosporin drugs to regulate, common drugs have cefuroxime and so on. 2. Prostatitis: when the patient suffers from prostatitis, the prostate gland will undergo pathological changes, and the semen may not be liquefied. 3. Endocrine disorders: Decrease in testosterone level caused by various reasons will affect the normal secretion function of the prostate gland and reduce the secretion of liquefaction factor, resulting in semen non-liquefaction. You can use testosterone, chorionic gonadotropin and other drugs to regulate under the advice of the doctor. All the above drugs need to pay attention to the side effects and adverse reactions of the drugs, please use the above drugs under the guidance of a doctor. There may be other reasons for sperm non-liquefaction, so patients are advised to go to the hospital in time and receive timely treatment to prevent adverse consequences.