The difference between primary hypertension and hereditary hypertension is that they are different in scope, and hereditary hypertension belongs to the category of primary hypertension. 1. Primary hypertension refers to hypertension with unknown pathogenesis. Hereditary hypertension has a clear etiology and pathogenesis, and gene sequencing can detect mutated genes. 2. Characteristics of primary hypertension: generally middle-aged onset, normal electrolytes and saline corticosteroid. Characteristics of hereditary hypertension: (1) Significant saline corticosteroid excess syndrome: (1) Short stature in childhood, unable to develop normally. (2) Severe hypertension, which can lead to organ damage at an early stage, manifested as polydipsia and polyuria. (iii) Low renin, low aldosterone, hyper salicorticoid, hypokalemia. (2) Pseudo-type II hypoaldosteronism: manifested by hypertension, hyperkalemia, but normal renal function. It may be combined with hyperchloremia, acidosis, hypercalcemia, hyponephrine, and hyperaldosteronism. (3) Aldosteronism such as glucocorticoid treatment: ① Autosomal dominant inheritance. (ii) Hypertension, alkalosis, and decreased blood potassium can occur at an early stage. Blood aldosterone increases and renin activity decreases. It can be corrected by glucocorticoid. (4) Liddle syndrome: autosomal dominant inheritance, hypertension, hypokalemia, and metabolic alkalosis can occur at an early stage. (5) Congenital adrenocortical hyperplasia: type IV and type V can lead to hypertension, type IV causes masculinization of girls and precocious puberty in boys. Type V can appear girls primary amenorrhea, boys sex organs can not be distinguished. The emergence of hypertension, should promptly seek medical attention to identify the causes, timely treatment, to avoid complications.