What are the methods of ovulation promotion? In vitro fertilization technology is increasingly used in the field of infertility, and for many infertile couples it is IVF that brings them a child’s innocent smile, the following is to explain the several methods of ovulation promotion, so that infertility patients have a deeper understanding of IVF. 1. Ovulation induction by estrogen: The principle is that high doses of estrogen can induce ovulation by increasing the secretion of luteinizing hormone in the pituitary gland when given for a short period of time. It can be given orally on day 8-10 of the menstrual cycle, 5 mg per dose, every 6 hours, for a total of 20 mg, or 2 mg of fastidious estrogen, divided into 24-hour doses. 2. Ovulation induction by sequential estrogen and progestin: For women with sporadic ovulation in general. Generally, endometrial withdrawal bleeding occurs 2-7 days after stopping the drug, which is one course of treatment. Clomiphene induces ovulation: It is suitable for functional amenorrhea, anovulatory dysfunctional uterine bleeding, luteal insufficiency and infertility caused by polycystic ovary syndrome with a certain level of estrogen in the body, and it can also help to restore normal menstrual cycle. It is administered as Clomiphene 50 mg once daily on days 5-9 of the menstrual cycle. In patients with amenorrhea, progesterone should be injected intramuscularly to induce withdrawal bleeding, and the drug should be started on the 5th day of bleeding to exclude uterine amenorrhea, and then clomiphene should be taken after the normal menstrual cycle is established, which can increase the efficacy. 4. Progestin induced ovulation: Fast estradiol (Gynecomastia tablets) 10 mg or progesterone 10 mg once daily on day 21 of the menstrual cycle for 5 days. Ovulation induction by combined estrogen and progesterone: take 0.03-0.05 mg of fast estradiol and 5-10 mg of megestrol orally once daily on day 5-25 of the menstrual cycle for 3-6 cycles and then stop. 5.Chorionic gonadotropin induced ovulation: In patients with mild pituitary and ovarian insufficiency, chorionic gonadotropin alone can be used to induce ovulation. Chorionic gonadotropin is injected intramuscularly on day 10 of the menstrual cycle, 1000-3000 units per day for 5 times. During the treatment, ultrasound examination should be done every 2 days to note the size of the ovaries. If excessive ovarian enlargement or polycystic changes are found, the drug should be stopped immediately. 6.Luteinizing hormone releasing hormone (LH-RH) to induce ovulation: It is suitable for anovulatory patients with hypothalamic malfunction but normal pituitary and ovarian function. However, the effect of ovulation induction with LH-RH alone is not ideal, but mostly combined with clomiphene or HCG and HMG. 7. Combined application of gonadotropin and dehydrocorticosterone to induce ovulation: from the 2nd day of menstruation, take oral dehydrocorticosterone 5 mg daily for 10 days; from the 5th day of menstruation, add clomiphene 150 mg daily for 5 days, and later inject intramuscular HMG 75-150 units daily. Continuously measure urinary estrogen, and stop about when urinary estrogen is significantly elevated; after 24 hours, inject 500-1000 units of HCG intramuscularly again. 8, Chinese herbal ovulation capsules to promote ovulation: this drug is the chief physician Wang Zhongmin developed to promote ovulation capsules Chinese medicine preparation, after years of use, clinically confirmed to have a better ovulation promotion effect. How to take this medicine: Take 5-6 capsules (0.45g per capsule) each time from the fifth day of menstrual cycle, 3 times a day for 10 days. In addition to its ovulation-promoting effect, the drug can also treat luteal insufficiency and is indicated for infertility such as anovulation, luteal insufficiency and low estrogen levels. The drug can be taken together with clomiphene and it can reduce the side effects of clomiphene. Experts warmly suggest: For IVF patients should choose a good hospital before performing the procedure, public tertiary hospitals are trustworthy, with perfect facilities and clinically experienced experts can be good preparation for improving the success rate of IVF.