Some patients are worried about the harm caused by ovulation drugs and request natural cycles or mild stimulation ovulation. For example, if the number of eggs retrieved in a single session is 4-5 (only one egg can be retrieved in a natural cycle), and the effective embryo rate is 50%, only 2-3 effective embryos can be obtained per treatment, and only 1 embryo transfer is possible at most. If there is no pregnancy, ovulation and egg retrieval will need to be repeated. The conventional ovulation protocol, on the other hand, uses more ovulation-promoting drugs than the former, but it also obtains a higher number of eggs per treatment and a correspondingly higher number of effective embryos. For example, the average number of eggs obtained with a conventional ovulation protocol is 10-12 eggs per treatment, and based on a 50% effective embryo rate, 5-6 effective embryos can be obtained per treatment, and if 2 embryos are transferred each time, there are 3 opportunities for transfer, which results in a high cumulative success rate (with 3 opportunities for transfer, approximately 80% of treated patients can become pregnant). In addition, the possibility of having multiple embryo transfer opportunities with one ovulation promotion and one egg retrieval is also beneficial in reducing patient suffering. In terms of economics and efficiency, the conventional ovulation protocol is also the most efficient, although of course the incidence of ovarian hyperstimulation syndrome is higher with conventional ovulation protocols than with mild stimulation protocols. However, clinicians are now becoming more experienced and the incidence of overstimulation is very low. Therefore, the decision of which ovulation promotion protocol to use depends entirely on the patient’s condition, and only an individualized treatment plan is the most appropriate for the patient.