Nearly half of the patients in depression will affect sexual function, manifested as low sexual function, or even no desire. Many people feel difficult to talk about it, and often consult the venereal disease department and urology department, but no organic lesions are found, mostly related to depression. Both men and women with depression can have low sexual interest and affect sexual function, which can lead to marital discord or being suspicious, easily causing family conflicts, and the patients themselves are very painful, and sometimes show irritability, annoyance, impulsivity, and even outbreaks of strong conflict with others.