Grade 2 hypertension is defined as a systolic blood pressure of 160 to 179 mmHg or a diastolic blood pressure of 100 to 109 mmHg. In the early stage of hypertension may be asymptomatic or symptoms are not obvious, with the prolongation of the course of the disease, the blood pressure continues to be at a high level, may appear dizziness, headache, memory loss, palpitation, chest tightness, numbness of the limbs and other discomforts. Secondary hypertensive patients need standardized antihypertensive treatment to reduce the incidence of hypertensive heart, cerebrovascular disease and mortality, according to the guideline guidance suggests that the general patient’s antihypertensive goal is 140/90mmHg or less, and for the combination of diabetes mellitus or nephropathy, the goal of blood pressure control is 130/80mmHg or less. Hypertension antihypertensive treatment is mainly through the improvement of lifestyle habits and antihypertensive drugs synergistic treatment, commonly used antihypertensive drugs such as nifedipine, propranolol, captopril, irbesartan, hydrochlorothiazide, etc., each drug has its own scope of application, the specific choice of drugs need to be based on the patient’s condition and the corresponding test results to determine the specialist.