Gastric cancer is the most common cancer among the malignant tumors of digestive tract, and its incidence rate varies greatly among different countries and regions. China is a high incidence area of gastric cancer, among which the northwest is the highest and Baoji is also a high incidence area. The detection rate of this disease has a tendency to increase year by year. Stomach cancer mostly occurs in people above 40 years old, and about two-thirds of them are aged 41-60, and the ratio of men to women is about 3.6:1. Etiology The etiology of the disease has not been fully elucidated, but according to epidemiological and etiological research, it is considered to be related to the following factors: 1. Exogenous factors: the development of stomach cancer is related to environmental factors, including food, soil, water, etc. Smoking, the incidence of gastric cancer is significantly higher than that of non-smokers. 2.Endogenous factors: According to statistics, the incidence rate in the family of gastric cancer patients is four times higher than that of the control group. Pre-cancerous diseases: refers to benign gastric diseases that can evolve into gastric cancer. Gastric ulcer, chronic gastritis, gastric polyp, residual stomach. Symptoms: The onset of disease is insidious. Early gastric cancer may be asymptomatic, or may only have mild upper abdominal discomfort, poor appetite, fatigue, etc., and there may be no local signs, so it is often misdiagnosed as chronic gastritis until the cancer develops to middle or late stage, and the following manifestations will appear one after another: 1. Upper abdominal pain Initially, it is hidden pain, then it gradually increases to moderate to severe, mostly occurs after meals, without interval, and cannot be relieved by taking acidulants. Gastric cancer patients often have loss of appetite, especially those who used to have good appetite, but recently they have a drastic decrease in food intake and progressive weight loss, mental atrophy, fatigue and weakness, all of which should be suspected. 3, gastrointestinal bleeding Mostly small amounts of vomiting blood or black stool, a few with acute upper gastrointestinal hemorrhage as the first symptom. 4.Progressive anemia A few patients present with anemia as the first symptom, mostly due to chronic progressive blood loss caused by cancer. Other symptoms may vary depending on the location, size and metastasis of the tumor, such as pancreatic cancer may cause swallowing difficulty at an early stage; pyloric cancer may cause pyloric obstruction; lung metastasis may cause cough and breathing difficulty; liver metastasis may cause liver pain and jaundice; bone metastasis may cause bone pain, etc. 1.Blood test There are often different degrees of anemia and increased blood sedimentation. 2.Fecal occult blood test Most of them are consistently positive. 3.Gastric fluid examination Gastric fluid may be mixed with blood or coffee-colored sediment. There is a lack of gastric acid. Lactic acid concentration is increased. 4.Barium X-ray examination is one of the important diagnostic methods. It is difficult to detect early gastric cancer, but the positive rate of barium meal can reach 90% in middle and late gastric cancer. 5.Fiber gastroscopy is an effective method for early diagnosis, and biopsy combined with cytological examination can improve the diagnosis rate of gastric cancer. Serological test Serological test for diagnosis of gastric cancer is one of the key issues of current research. Treatment The treatment effect of gastric cancer depends on whether it can be diagnosed at an early stage, and medical treatment can only reduce symptoms and support treatment. Surgery is the most effective method to cure gastric cancer. It should be removed as much as possible for patients with middle and late stage. 2.Chemotherapy Anti-cancer drugs are often used to supplement surgical treatment, and are used before, during and after surgery to inhibit the spread of cancer cells and kill the remaining cancer cells, so as to improve the surgical efficacy. Combination of drugs is generally considered to be more effective than chemotherapy alone. 3.Radiation therapy has certain efficacy. 4.Immunotherapy Use tumor seedlings made of cancer cells and immune enhancers to improve the patient’s specific immunity against cancer, such as gastric cancer-specific transfer factor and interferon.