Anti-inflammatory drugs do not exist which is the safest, the more commonly used anti-inflammatory drugs are cephalosporin antibiotics, penicillin antibiotics, quinolone antibiotics, etc., but do not rule out the use of each anti-inflammatory drugs after a certain number of side effects, should be combined with their own situation to choose. 1. Cephalosporin antibiotics: representative drugs are cefixime, cefaclor, cephradine, etc.. Long-term use of these antibiotics may cause anaphylactic reactions, resulting in skin rashes, itching, or eosinophilia, and occasionally anaphylactic shock may occur. 2. Penicillin antibiotics: the more representative drugs are Chlorazol Penicillin, Penicillin V Potassium, Amoxicillin, Ampicillin and so on. Long-term use of penicillin antibiotics may cause gastrointestinal reactions, such as nausea, vomiting, etc. Some patients will have neurological reactions, such as abnormal nerve excitation. 3. Quinolone antibiotics: for example, norfloxacin, levofloxacin, ciprofloxacin, etc. Long-term use of quinolone antibiotics may cause bacterial imbalance, easy to cause diarrhea. Some patients are susceptible to hypersensitivity reactions with long-term use, or have central nervous system reactions, which can cause blood sugar disorders and photosensitivity in severe cases. If you need to use this kind of antibiotic, you should follow the doctor’s instructions in accordance with the indications, not arbitrary use of drugs, but also need to pay attention to the course of treatment.