Ascending colon mucosal bulge is generally colon polyps, whether it is serious needs to be based on the size and shape of the polyp and pathologic biopsy results comprehensive decision. Hyperplastic colon polyps are the most common, often multiple, usually directly less than 5mm, do not need special treatment. If it is larger than 5mm and less than 2cm, it is a pedunculated polyp, which can be considered for endoscopic resection, and pathologic biopsy can be performed after resection for further clarification. Wide base polyps can also be endoscopically resected, but need to wait for the return of pathologic biopsy results after resection. A small portion of the ascending colon mucosal bulge, pathology biopsy suggests colonic malignant tumor, this time need to further improve the relevant examination, exclusion of metastasis, according to the situation of the development of treatment plans for early treatment. Ascending colon mucosal bulge for endoscopy, must be combined with pathological results of comprehensive analysis.