Small pimples on the face generally refer to acne, and acne can be treated with topical medications, physical therapy and systemic medications. 1. Topical medication: Topical medication for acne mainly includes retinoids such as adapalene and retinoid ointment, antibacterial medication such as fusidic acid and clindamycin, and other medications such as benzoyl peroxide and azelaic acid, which also have the effect of improving acne. 2. Physical therapy: Physical therapy mainly includes photodynamic, red and blue light. For the formation of post-inflammatory discoloration and scarring after acne healing, it can be improved by laser. 3. Systemic medication: Systemic medication for acne includes antibiotics, such as minocycline and doxycycline; for severe cases, oral isotretinoin or glucocorticoid drugs can be taken. It is recommended that patients go to a regular medical institution, identify the cause of the disease in a timely manner, and follow the doctor’s instructions to use medication to avoid delays in the condition.