Cachexia, also known clinically as cachexia, is a syndrome of extreme emaciation, skin and bones, skeletal appearance, anemia, weakness, complete bed rest, inability to care for oneself in life, extreme pain, and systemic organ failure. Cachexia is mostly caused by cancer and other serious wasting diseases. The pathogenic factors cause changes in the body’s metabolism through various pathways in the body, resulting in a weakening of the oxidation process in the body, accumulation of oxidation incomplete products, and inability of nutrients to be fully utilized by the body. Cachexia is seen in a variety of diseases, including tumors, severe trauma, post-surgery, malabsorption, and severe sepsis. Among them, cachexia associated with tumors is the most common and is called tumor cachexia. If cachexia occurs, the best approach is to treat the primary disease while focusing on supplementing the patient’s nutrition, promoting appetite and reducing wasteful metabolism.