Half-tablet hormones are not usually stopped outright, but are decided in consultation with a doctor, depending on the type of disease, condition and type of medication taken. In most cases, hormones need to be tapered and stopped slowly. Some of them need to be taken for life and cannot be stopped. Certain diseases require hormone medication, which must be used in strict accordance with the doctor’s instructions, when the disease gradually improves, according to the doctor’s instructions to start decreasing the amount of medication, and then slowly stop using the drug. Discontinuing the medication too quickly may result in adverse reactions or a relapse of the disease. Hormonal drugs have certain adverse reactions, different diseases use different, to strictly grasp the indications. Such as glucocorticoids may be stabilized with the gradual discontinuation of drugs; and hypothyroidism, thyroxine supplementation may require lifelong medication, so that even half a tablet can not be discontinued. Hormone application should be carried out strictly according to the doctor’s instructions, and whether to stop the drug should be decided after consulting the doctor.