People can easily get infected by herpes virus when they are on fire, have a cold or other low immunity, or make the virus lurking in the mouth flare up, resulting in blistering of the lips. For treatment, you can take antiviral drugs, such as antiviral oral solution, Pu Dilan Punch and Banlangen Granules, etc. Acyclovir ointment can be applied to the area of the blistered lips. Erythromycin ointment can be applied once the blisters break down and cause secondary bacterial infection of the eruption. If the blisters appear in the mouth or cheeks, you can gargle with light salt water, chlorhexidine mouthwash or tinidazole mouthwash. Oral fire blisters can take heat-clearing and fire-removing herbs or fire-removing teas, such as niu huang detoxification tablets, fire-clearing tablets, honeysuckle tea and chrysanthemum tea. In addition, drink more water, eat more fresh fruits and vegetables, diet to light food, ensure adequate rest and sleep, enhance the body’s resistance.