Herpes zoster is caused by the varicella-zoster virus, which is usually latent in the posterior spinal root neurons. When the body’s resistance is low, the virus can grow and multiply again and move along the nerve fibers to the skin, causing intense inflammation of the invaded nerves and skin. Therefore, herpes zoster is the skin symptom of inflammation of the nerves after recurrent attacks of herpes I virus, which is a symptom; while the intrinsic virus attack on the nerves is the root cause of the posterior neuralgia, which is the cause of the disease! Most doctors in the clinic tend to give active treatment for skin herpes and ignore the timely repair of the intrinsically damaged nerves, resulting in patients with skin herpes well, but the pain is still developing, which is a typical headache and foot treatment! As a patient and the patient’s family, suffering from shingles, it is important to be aware of what kind of herpes is prone to leave behind severe neuralgia. Here we summarize several ideas based on clinical experience to help you make a judgment and facilitate timely consultation: 1. Age factor. Patients older than 60 years of age who have herpes zoster should be promptly seen by the pain department. The reason why the age factor is put in the first place, this is because the occurrence of herpes zoster sequelae neuralgia is closely related to age, the underlying cause is the problem of low immunity, the older you are, the worse the immunity, once the herpes occurs, the more difficult it is for the virus to cause damage to the nerves to repair itself, the greater the probability of occurrence of sequelae neuralgia, the heavier the degree of pain and the longer it lasts; 2, the size of the herpes attack, the The larger the area, the easier it is to scab and form scar tissue, the greater the probability of post-herpetic neuralgia and the more severe it is; 3. The more likely it is to have severe neuralgia after the herpes has healed, the more likely it is to have severe neuralgia after the herpes has healed, requiring early intervention; 4. Patients with uremia have a significantly higher probability of developing postherpetic neuralgia. These patients either need surgery, systemic chemotherapy or local radiotherapy, or uremic patients need continuous immunosuppression after kidney transplantation, and the systemic immunity continues to decline significantly, which can easily lead to herpes attacks, and the virus is so destructive to the nerves that the ability to repair itself is almost lost, and the probability of post-herpetic neuralgia is extremely high; 6. The probability of postherpetic neuralgia is higher in patients. Herpes zoster and post-herpetic neuralgia is a disease that requires a race against time! Through our daily work, we come into contact with a large number of patients who, due to the lack of understanding and attention to herpes attacks, often seek medical help in a hurry and repeatedly seek medical help between dermatology, traditional Chinese medicine and neurology without success, before finally thinking of pain medicine and not getting timely and correct treatment, missing the best nerve repair period, which is a great pity! Therefore, we hope that through the several warning factors summarized in this article, more shingles patients and their family members will understand this disease, take the right number, make a judgment at the first time, and visit the pain department in time for a specially trained pain doctor to provide you with various nerve repair means including nerve block, and really relieve the disease from its cause.