Genital herpes is a sexually transmitted disease caused by the herpes simplex virus (HSV), mainly HSV-2 and, to a lesser extent, HSV-1. It is one of the common STDs. Genital herpes can recur and has a major impact on the health and psychological well-being of the patient; it can also infect newborns through the placenta and birth canal, leading to congenital infection in newborns. Therefore, this disease is one of the more serious public health problems and should be given attention for its effective prevention and treatment. The characteristic multinucleated giant cells or intranuclear viral inclusion bodies can be seen under the microscope. Herpes simplex virus antigen is detected by direct fluorescence with monoclonal antibody or ELISA. 3.Viral culture Specimens were taken from the lesions for viral culture and found to have herpes simplex virus and cytopathic lesions. 4. Nucleic acid detection HSV-2 nucleic acid is detected by polymerase chain reaction (PCR) and other methods. Treatment: Genital herpes is mainly treated with antiviral therapy. The purpose of treatment is to relieve symptoms, reduce pain, shorten the course of the disease and prevent secondary infection. The current treatment methods are not yet able to achieve complete clearance of the virus and eliminate recurrence. 1. General treatment (1) Mainly to keep the local clean and dry. It can be washed with isotonic saline every day, and painful people can take oral painkillers and give mental comfort. (2) Complicated bacterial infection, can be used externally antibiotic cream. (3) For obvious local pain, topical 5% lidocaine hydrochloride ointment or oral painkillers can be used. (4) Psychological support, explain the nature of the disease, the causes of recurrence and how to treat and deal with it, to enhance confidence in fighting with the disease. 2. Antiviral drug treatment The recommended treatment regimen includes: acyclovir, orally, 5 times a day; or acyclovir, orally, 3 times a day; or valacyclovir, orally, 2 times a day; or famciclovir, orally, 3 times a day. In the case of primary genital herpes, the course of treatment is 7 to 10 days; in the case of recurrent genital herpes, the course of treatment is 5 days. Frequent recurrences require a longer course of treatment at a lower dose.