Colds generally do not lead to leg pain, when there are symptoms of colds and leg pain, you need to consult a doctor to clarify the cause of the disease and then choose the appropriate medication, such as cefixime, diclofenac sodium, ibuprofen capsules and so on. 1. Cold: caused by viral infection, generally do not antiviral treatment, mainly symptomatic treatment, such as nasal congestion and runny nose can use pseudoephedrine and other serious. 2. leg pain: the cause of leg pain may be lumbar disc herniation, lower extremity venous thrombosis, knee arthritis, etc., you can take diclofenac sodium, ibuprofen capsules to relieve pain, rivaroxaban and other drugs to dissolve the thrombosis and anticoagulation, or with acupuncture, physiotherapy and other ways to alleviate the symptoms, and if necessary, surgical treatment. It is recommended to improve the relevant laboratory tests to clarify the cause of the disease in a timely manner, under the guidance of the doctor reasonable use of medication, the above drugs should not be used without authorization, to avoid serious adverse reactions.