Whether blood creatinine 150umol/L is kidney disease depends on the reason of creatinine increase. If it is caused by physiological reasons such as high muscle content or eating more meat, it is not kidney disease at this time; if it is caused by pathological reasons such as acute kidney injury or chronic renal insufficiency, it is kidney disease. Normal serum creatinine ranges from 53 to 106 μmol/L in men and 44 to 97 μmol/L in women. Therefore, creatinine 150μmol/L is mildly elevated. 1. Physiological reasons: some patients with elevated creatinine may be due to their high muscle content, or usually eat more meat, exercise more caused by routine urinalysis and ultrasound of the urinary system and other related tests do not see any abnormality, and after adjusting the lifestyle creatinine may return to normal, this case is not nephropathy. 2. Pathological reasons: acute kidney injury caused by various reasons, or glomerulonephritis, diabetic nephropathy, hypertensive renal damage and other diseases leading to chronic renal insufficiency, may lead to creatinine increase, this case is considered to be nephropathy, and need to be treated according to the cause. If patients find that blood creatinine is elevated, it is recommended to go to regular hospitals in a timely manner, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy under the guidance of the doctor. Acute kidney injury is a disease caused by a variety of reasons for a short period of time decline in renal function, such as serious infections, hemorrhage, etc. Generally, after active treatment and correction of the cause, renal function can be restored to normal. Chronic kidney disease is the final result of the development of various renal diseases, which can be divided into 5 stages, end stage that is uremia stage, when blood creatinine to 150umol/L, belongs to the chronic kidney disease stage 2-3, this time should be actively treating the primary disease, enhance the physical fitness, avoid the use of nephrotoxic drugs, control the intake of protein, to slow down the progress of chronic kidney disease. When the blood creatinine is 150umol/L, you should go to the nephrology department of regular hospitals, and be diagnosed and treated after evaluation by specialized hospitals.