Thumb bone pain is caused by osteoarthritis, rheumatoid arthritis and gout. 1. Osteoarthritis: the cause of osteoarthritis is not clear, its occurrence is usually related to trauma inflammation, age, as well as obesity and hereditary factors, the main symptoms of joint pain and stiffness, so there will be the symptoms of thumb bone pain. 2. Rheumatoid arthritis: rheumatoid arthritis cause is not clear, but some studies have found that it may be autoimmune as well as infected genetics and smoking reasons related to the main symptoms of joint pain, as well as joint dysfunction and joint deformity, so there will be symptoms of thumb bone pain. 3. Gout: Gout is usually associated with eating foods high in purines or being overweight, leading to excessive uric acid production or reduced excretion, making blood uric acid increase, usually with the symptoms of red, swollen and painful toes. Thumb bone pain is recommended to actively go to the regular hospital, a clear diagnosis, and then according to the situation using the appropriate solutions.