There are many factors that affect the occurrence and development of bones, and the more common ones are as follows: First, hormone levels, there are many hormones that affect growth and development, including growth hormone, thyroid hormone, parathyroid hormone, glucocorticoid hormone, estrogen and so on. Once these hormones become abnormal, it will obviously affect the occurrence and development of bone. Secondly, dietary factors are also crucial to the growth and development of bone, without a good diet, there is no way to promote the normal and good development of bone. Third, exercise factors, for the growth and development of bone is also vital, good sports will stimulate bone growth. Fourth, there are some acquired diseases, especially bone tumor disease will seriously affect the occurrence and development of bone.