Low estrogen in women is usually seen in menopausal women, and patients’ symptoms include the following: 1. general symptoms: such as hot flashes and night sweats, insomnia and forgetfulness; 2. genitourinary system: when the genitourinary system is atrophied and dry, patients are prone to urinary tract infections and vaginitis; 3. skin: manifested as skin wrinkling, dryness and anthroposis; 4. bones: low estrogen is prone to osteoporosis, resulting in symptoms of low back pain; 5. cardiovascular diseases.