1. Is the pathological diagnosis of lymphoma more important compared to other tumors? First of all, pathological diagnosis of all tumors is very important because clear pathological diagnosis is a prerequisite for treatment and prognosis. The pathological diagnosis of lymphoma is more complicated compared with other tumors, because in addition to the two main types of non-Hodgkin and Hodgkin lymphoma, there are more than 50 subtypes of non-Hodgkin lymphoma, and the clinical characteristics, treatment and prognosis of different subtypes are different. Therefore, the pathological diagnosis of lymphoma can be relatively complicated and often requires the removal of complete lymph nodes to improve the accuracy of diagnosis and reduce the rate of misdiagnosis. 2.In addition to pathological diagnosis, what other tests are needed before treatment of lymphoma? After pathological diagnosis, it is necessary to clarify the stage, that is, the location and extent of the tumor in the body. The main means to clarify the staging is imaging examination, among which CT is the most widely used. It should be emphasized here that because lymphoma is a systemic disease, the scope of CT scan should cover the whole body, including the neck, chest, abdomen, pelvic area, and intracranial area if necessary, during the first staging examination, and enhanced CT should be done as much as possible. patients with good financial ability can choose PET-CT examination, which has the potential to detect lesions that cannot be distinguished by CT and help more accurate staging. MRI has higher resolution than CT for tumors in the central nervous system and head and neck regions. In addition to comprehensive imaging, bone marrow aspiration and biopsy are included, as lymphoma more often involves the bone marrow. Some patients also need lumbar puncture to identify whether there is intracranial or meningeal involvement. 3. Is the first chemotherapy regimen for lymphoma particularly important? Yes. Because lymphoma is a drug curable tumor, whether it can be cured or not, proper first treatment is very critical. Once relapse occurs, the cure rate is significantly lower. The efficacy of the first treatment is related to a combination of factors such as drug combination, drug strength, management of adverse reactions and reasonable combination with radiotherapy.