It is recommended to use safflower oil after 30 minutes after the sprain. During this time, patients are advised to apply cold compresses to the sprained area as soon as possible. Generally, patients are advised to apply cold compresses in the form of ice or cool towels. After a sprain, a series of localized subcutaneous bleeding and sterile inflammation can occur. If the early use of safflower oil and assisted massage, may lead to increased local swelling, in this case it is recommended that the patient first use cold compresses to make local vasoconstriction, and inhibit local sterile inflammation. After the cold compresses are applied, safflower oil is then used. In general, patients are advised to apply safflower oil only topically and not to massage it. The sprained limb should be padded higher with a pillow during nighttime sleep, and if the patient has an elastic bandage, ankle brace, or wrist brace, this type of brace can also be worn. If the patient does not experience significant relief within 2-3 days of using such a method, he or she must continue to visit an orthopedic clinic to clarify the specific location and extent of the injury, and then target treatment.