Vaginal opening itching is highly suggestive of female perineal infection, specific treatment measures are as follows: 1, mild infection: patients are advised to strengthen personal hygiene habits to strengthen sexual hygiene habits, diligent bathing, diligent change of underwear as the main, if necessary, you can apply topical medicines, such as erythromycin ointment, chitosan sprays or female lotion, for the control of mild perineal infections, has a better effect; 2, serious infection: if the In addition to vulvar itching, the patient has developed urinary tract problems, such as frequent urination, urgency of urination, burning sensation of urination, itching sensation and tingling sensation. At this time, it is recommended that the patient drink more water and keep the water intake at 2000-3000ml/d. At the same time, oral antibiotics can be taken, such as cephalosporins, quinolones or phosphomycin antibiotics. In conclusion itching of the vulva and vaginal opening should not only be treated as a separate localized infection, but the risk of cross-infection to the urinary tract that may occur at a later stage should also be taken into account, leading to comprehensive advice and treatment.