Anti-cancer, anti-tuberculosis drugs, anti-epileptic drugs and other drugs with low safety will affect the preparation for pregnancy, and it is recommended that you should consult your physician before using the drugs during the preparation for pregnancy. Preparation for pregnancy can not be arbitrary use of drugs, clinical according to the pregnancy safety of drugs are divided into A, B, C, D, X grade, preparation for pregnancy is not recommended to take C, D, X grade drugs, the sperm and eggs have a greater impact, especially methotrexate, cyclophosphamide and other anticancer drugs, phenobarbital, valproate and other anti-epileptic drugs, rifampicin, isoniazid and other antituberculosis drugs. While Class A drugs such as vitamins and folic acid are safer and can be taken during preparation for pregnancy with the permission of your doctor.Class B drugs such as penicillin and cefixime can also be taken if permitted by your doctor. Both men and women should undergo a comprehensive examination before preparing for pregnancy. If they suffer from tuberculosis, epilepsy, or infectious diseases, they should be actively diagnosed and treated, and then consider preparing for pregnancy after their condition is stabilized and their physical condition permits. If there is no clear indication for the use of drugs during the preparation for pregnancy, it is generally not recommended to use drugs.