Rounded hypodense shadow 5x4mm in the liver can be seen in liver cysts, hepatic hemangiomas, hepatic cysticercosis, primary hepatocellular carcinoma and other diseases. It is recommended that the patient undergoes further examination, such as ultrasound, enhanced CT, MRI, etc., to observe the lesion site from imaging. If a tumor is considered, tumor marker tests, such as alpha-fetoprotein (AFP), etc., are also needed; in addition, a puncture biopsy can be performed to determine histologically what the space-occupying lesion in the liver is. When the patient has intrahepatic hypodense shadow, it is necessary to improve the enhanced CT and nuclear magnetic examination of the liver. In addition, if the patient has physical discomfort, such as loss of appetite, jaundice, subcostal pain and other manifestations, it is necessary to go to the hospital in a timely manner for follow-up, if necessary, surgery or other standardized treatment.