Levamlodipine benzenesulfonate can and tadalafil can be taken together, but the combined use has the possibility of lowering blood pressure, the use of both drugs should be under the supervision of a doctor. Levamlodipine benzenesulfonate is a dihydropyridine calcium channel antagonist, which can lower blood pressure and anti-angina. Tadalafil is a cyclic guanosine monophosphate-specific phosphodiesterase inhibitor that acts as an erection promoter in response to sexual stimulation. There are no clinically significant drug interactions between levamlodipine benzenesulfonate and tadalafil, and the two drugs can be taken together, although there is a potential for lowering blood pressure with combined use. Levamlodipine besylate should not be used in people with a history of allergy to this drug; there may be edema, fatigue, insomnia, palpitations, dizziness and other discomforts. Tadalafil should not be combined with nitrates such as isosorbide dinitrate; use with caution in patients with heart disease. There may be adverse reactions such as headache, flushing, nausea, myalgia, and back pain. The medication should be used as prescribed by the doctor.