Mean red blood cell volume refers to the average of all red blood cell volumes, and the normal reference range is 80~100fl. The size of the mean red blood cell volume has clinical significance for further diagnosis and treatment of patients with anemia.
1. Anemia patients, if the average red blood cell volume is small, suggesting microcytic anemia, clinically seen in iron deficiency anemia, iron granulocytic anemia, etc., need to further improve the ferritin examination.
2. If the average red blood cell volume is normal, it suggests that the patient is an orthostatic anemia, and the possibility of hematologic diseases is high, such as acute leukemia, non-Hodgkin’s lymphoma, and so on, and it is necessary to improve the bone marrow puncture, biopsy and other tests.
3. If the average red blood cell volume becomes large, suggesting macrocytic anemia, on the one hand, it is necessary to improve the examination of folic acid and vitamin B12 to exclude megaloblastic anemia. On the other hand, it is necessary to improve the bone marrow aspiration and biopsy to exclude myelodysplastic syndrome.
For patients with anemia, it is necessary to combine the average red blood cell volume to further determine the possible types of disease, so as to carry out the next diagnosis and treatment under the guidance of physicians.