Children with bone age advancing by 2 years can be treated with supplemental nutrition, increased exercise, and growth hormone if necessary. 1. Supplementary nutrition: Children’s growth and development need to be supplemented with sufficient nutrition. Children can be trained not to pick food and not partiality, develop good habits to eat more vegetables and fruits, to ensure balanced nutrition. 2. Increase exercise: Long-term adherence to running and basketball can promote the secretion of pituitary hormones; help to stretch the joints, the bones and muscles of the whole body can be exercised, stretching ligaments, potentially helping children grow taller. 3. Treatment with growth hormone: mainly take recombinant human growth hormone replacement therapy, subcutaneous injection, the younger the age, the better the effect. Children with advanced bone age need to take means of intervention and standardized treatment under the guidance of doctor’s advice.