Stubborn eczema usually refers to chronic eczema, for patients with chronic eczema, general treatment, medication, physical therapy and other methods can be used to improve. 1. General treatment: chronic eczema patients need to avoid allergies or irritants, avoid scratching. Appropriate moisturizing emollients can be used to keep the skin moisturized. 2. Medication: For the treatment of chronic eczema, local application of glucocorticosteroid preparations, such as dieldrin, dexamethasone, trimethoprim, etc., have anti-inflammatory and anti-allergic effects. If itching is obvious, oral antihistamines such as loratadine and cetirizine can be taken. When the lesions are generalized and severe, oral medications such as compound glycyrrhizin, tretinoin, paeonia lactiflora, cyclosporine, etc. can be taken together. 3. Physical therapy: patients can also use physical therapy, the use of ultraviolet light therapy, such as narrow-spectrum medium-wave ultraviolet irradiation, chronic eczema has a better therapeutic effect. For patients with chronic eczema, they should go to the doctor for standardized treatment, and the medication should be prescribed by the doctor.