High thyroid peroxidase antibody may be caused by certain autoimmune thyroid diseases, such as Hashimoto’s thyroiditis, Graves’ disease, postpartum thyroiditis, atrophic thyroiditis, etc. In addition, certain autoimmune diseases, such as rheumatoid disease, systemic lupus erythematosus, etc., may also lead to high thyroid peroxidase antibody. Serum thyroid peroxidase antibody is usually less than 60IU/ml, due to the different testing methods and reagents, the reference indexes are different in different hospitals and need to be analyzed specifically. If high thyroid peroxidase antibody occurs, you should go to the hospital in time, complete the relevant examination to clarify the cause of the disease, and avoid unauthorized use of medication under the guidance of the doctor to treat the symptoms.