Male syphilis is not always completely cured. Whether male syphilis can be completely cured or not is mainly determined by the type of syphilis and the duration of treatment and whether the medication is standardized. Syphilis is divided into stage I syphilis, stage II syphilis, and stage III syphilis; after men are diagnosed with syphilis, there is no difference in treatment with female syphilis, and the preferred drug is penicillin. 1. Stage 1 and 2 syphilis: men with stage 1 and 2 syphilis (within two years of the disease) can be completely cured through the use of penicillin therapy plus regular follow-up, and no sequelae will be left after the cure. 2. Stage III syphilis: Stage III syphilis refers to syphilis with a disease duration of more than two years and a variety of complications, such as violation of the cerebrospinal fluid leading to epilepsy, dementia; violation of the joints caused by joint deformity, joint enlargement, pain, etc.; violation of the cardio-cerebral blood vessels leading to cardiac valvular insufficiency, myocardial infarction, and other serious sequelae. Although the syphilis pathogen can be removed, but the organ damage that has been formed can not be reversed, and can not achieve the purpose of clinical cure. Whether male syphilis can be completely cured with the treatment time and whether the active standardized treatment, it is recommended to find syphilis timely and actively seek medical treatment.