If the pain is severe and unbearable, pain relief can be achieved by using antispasmodic drugs such as scopolamine and magnesium sulfate. 2. If the pain is severe and unbearable, pain relief drugs such as pethidine and morphine can be used. 3. If the pain is unbearable, surgical treatment is necessary. If the stone is in the bile duct, ERCP can be done, and if the stone is in both kidneys, transcystic or laparoscopic surgery can be performed to remove the stone. In addition, patients should drink water regularly, urinate more often, eat a light diet, and avoid foods that can produce stones.