The pain of the stone is related to the position of the body, but it is not always worse or less painful when lying down or standing up, but it is related to the part of the ureter that is obstructed by the stone. If the stone causes complete obstruction of the ureter, the pain will not change regardless of the position of lying down or standing up, but will be persistent. However, for stones in the kidneys, the pain may be more likely to occur because the stone is obstructing the renal pelvis and ureteral junction when lying down. The pain may be mildly relieved when the stone leaves the site of obstruction and enters the calyx or renal pelvis when standing and moving. For example, stones in the bladder area are sometimes easily obstructed in the urethra during urination and produce acute pain, but the pain may be relieved when the stone leaves the urethra after lying down or standing up. So the stone is not absolutely standing will be aggravated or alleviated, but with the location of the stone is related to, such as change of position after the stone left the site of obstruction, then the general pain will be reduced. However, if the stone is more likely to become obstructed in a narrow area such as the renal pelvis or ureter after a change in position, the pain will increase.