Choledocholithiasis pain is strong at night is mainly due to neurological factors, food factors and so on.
1. Neurological factors: the vagus nerve of the human body is relatively excited at night, which will stimulate the gallbladder to contract. In addition to the choledocholithiasis, it can further increase the internal tension of the gallbladder, thus making the pain worse.
2. Food factors: in the evening diet is generally more abundant, greasy food is relatively more, and in the meal is usually soon after the rest. At this time, the fat in the diet can stimulate the intestinal mucosa to release a kind of substance that promotes the contraction of the gallbladder in order to promote digestion and absorption, so it will also aggravate the pain of the stones.
As a result, stones are usually more painful at night, and if stones recur with severe pain, it is recommended to seek medical attention for standardized diagnosis and treatment as soon as possible.