Large hard and painful bumps on the forehead may be caused by trauma, acne, folliculitis, sebaceous cysts and other diseases. It is recommended to take good care of the affected area, and if necessary, give topical medication, oral medication, or can be treated by surgery. 1. Trauma: localized by external force, such as falling and touching the forehead, resulting in localized hard bumps and pain. If the hematoma is caused by infection, hot salt packs can be applied externally to promote the disappearance of hard lumps. More serious hard lumps are treated by surgical excision and suturing if necessary. 2. Acne: Hard lumps with pain caused by acne are considered to be related to infection. You can take roxithromycin and doxycycline orally, and apply Longzhu ointment externally to promote the elimination of pus. 3. Folliculitis: Folliculitis is mostly related to bacterial infection, which can also cause local redness, swelling and pain. Anti-infective drugs can be given, such as fusidic acid ointment, mupirocin ointment, erythromycin ointment, oral erythromycin, amoxicillin and other drugs. 4. Sebaceous cysts: The sebaceous glands in the forehead secrete exuberantly, and the ducts are blocked, forming sebaceous cysts, resulting in localized hard bumps and pain. It is recommended not to squeeze with hands to avoid infection, and if necessary, discharge the contents through surgical incision. To summarize, there are more reasons that lead to large bags and hard bumps on the forehead. It is recommended not to deal with it on your own, but to go to the dermatology department of the hospital for examination and ask the doctor to deal with the affected area.