Blisters on the lips may be caused by improper diet, labial inflammation, herpes simplex, trauma, etc. They can be improved by rubbing compound dexamethasone acetate cream, gentamycin ointment, acyclovir ointment, erythromycin ointment and other medications under the guidance of a doctor. 1. Improper diet: If you overeat spicy and stimulating food, it may lead to blisters on the lips. You need to regulate your diet, avoid spicy and stimulating foods, drink more water or eat more vegetables and fruits, and rub the compound dexamethasone acetate cream and other drugs to improve. 2. Lipitis: Lipitis may be caused by allergy, when the patient is in contact with allergens, it may make lipitis recur, which leads to the phenomenon of blisters on the lips. It can be improved by medications such as gentamycin ointment and mupirocin ointment. 3. Herpes simplex: When blisters appear on the lips, they may also be caused by herpes simplex virus infection. It can be improved by rubbing medicines such as acyclovir ointment and famciclovir ointment. 4. Trauma: If you accidentally bite your lip or burn it, it can easily lead to blisters on the lips. Erythromycin ointment can be rubbed to anti-inflammatory treatment. The blisters on the lips do not exclude other causes, the patient should go to the hospital in time, clear cause of the disease in the doctor’s guidance to choose the appropriate treatment.