Numbness in the hands and feet after anger usually does not lead to particularly serious consequences, but the specific situation should be judged according to the patient’s age and previous underlying diseases. If the patient is an elderly patient with a past history of hypertension or diabetes, the patient should be alerted to the possibility of acute cerebrovascular disease if there is numbness in the hands and feet after anger along with weakness in the limbs, and a cranial CT or magnetic resonance examination should be performed to clarify. If a young female patient has numbness in the hands and feet after anger, ask the patient if she has a past history of anxiety, if she is sensitive and suspicious, and if she is prone to nervousness, if she repeatedly has numbness in the hands and feet after anger, she should be alert to the possibility of acute stress disorder, and in severe cases, the patient may have limb twitching.