The reasons why bile does not flow from drainage tube of cholangiocarcinoma may include blockage of drainage tube, detachment of drainage tube, and the original bile duct is smooth and bile is normally drained into intestines on its own. If the drain is blocked, saline can be injected to recommunicate it; if the drain is dislodged, it can be reintroduced or removed according to the situation; if the bile duct is open, there is no need for special treatment. 1. Drainage tube blockage: blood clots, infected bile or pus flocculent, drainage tube twisted into an angle, etc., caused by drainage tube obstruction, bile drainage is not smooth, we can use a syringe to inject saline to confirm and improve the degree of smoothness; if necessary, we need to relocate the tube. 2. Drainage tube dislodgement: if the drainage tube is found to be dislodged from the bile duct to the abdominal cavity through examination, it is usually necessary to re-install the tube; if the bile duct is basically open and there is not much exudation from the abdominal cavity according to the condition of the patient, the patient can pay attention to observation until the drainage tube is completely removed. 3. If the original bile duct is smooth and the bile is normally drained into the intestines on its own: since the bile has flowed into the intestines without being drained out through the drainage tube and there is no abnormal situation, attention can be paid to observation and no special treatment is needed. If bile does not flow from the drainage tube of cholangiocarcinoma, it is necessary to make comprehensive judgment according to the clinical observation, the situation of leaving the drainage tube in the operation, and the results of CT, ultrasound, nuclear co-magnetism or imaging examination such as drainage imaging, etc., so as to clarify the cause. The role of bile duct drainage is very important, and the discovery of abnormalities should be promptly notified to the physician for treatment.