There is no record about the course of treatment in the drug’s instruction or pharmacopoeia. Diosmin tablets have been shown in many experiments that no clear complications or side effects were seen after about one month of application, and no clear side effects were seen when applied in overdose. Therefore, Diosmin can be considered for long-term use based on the above conclusions. The main treatment of Diosmin is varicose veins and hemorrhoids, in both cases the recovery of the venous valves and the recovery of the elasticity of the vein walls takes a longer time. Therefore, if there are no significant side effects, it is recommended to take Diosmin tablets orally for a long time, and in case of complications or side effects it is recommended to discontinue them.