Insulin and glucagon are both secreted by pancreatic endocrine cells and are important hormones for regulating blood glucose. The relationship between the two is as follows: First, the secreting cells are different, insulin is secreted by pancreatic beta cells and glucagon is secreted by pancreatic alpha cells. Insulin is the only hypoglycemic hormone in the body. Insulin can promote the synthesis of protein, fat and glycogen and inhibit the breakdown of protein, fat and glycogen, thus lowering the blood glucose level. Glucagon is the opposite of insulin and can promote the breakdown of glycogen and raise blood sugar. Third, the response to blood glucose is different. When blood glucose rises, the body promotes insulin secretion and inhibits glucagon secretion. When blood sugar decreases, the body will experience a decrease in insulin concentration and an increase in glucagon concentration, thus maintaining the dynamic balance of blood sugar, so insulin and glucagon are important hormones for maintaining the dynamic balance of blood sugar.