Common causes of elevated serum alkaline phosphatase include liver and gallbladder diseases, bone diseases, and other disorders. Elevated alkaline phosphatase can also be seen in growing children and women in the later stages of pregnancy.
1. Hepatobiliary diseases: various kinds of intrahepatic and extrahepatic bile duct obstruction, cirrhosis, etc. Alkaline phosphatase can be significantly elevated.
2. Bone diseases: fibrous osteitis, rickets, osteochondrosis, osteoblastoma, fracture healing, alkaline phosphatase can be seen elevated.
3. Other diseases: malnutrition, severe anemia, heavy metal poisoning, gastric ulcer, hyperparathyroidism, renal insufficiency, etc., alkaline phosphatase can also be seen elevated.
Increased serum alkaline phosphatase activity is mainly related to bone growth, pregnancy, maturation and postprandial secretion of fats, and under normal circumstances, it can also be seen elevated in children during the growth period and women in the later stages of pregnancy.
Serum alkaline phosphatase 500 or more should identify the cause of the disease, timely treatment, daily attention to diet and healthy, develop good habits.